![]() ![]() Lupron - What does it do to women’s health? (2008).Reevaluating response and failure of medical treatment of endometriosis: A systematic review. ![]() You can learn more about how we ensure our content is accurate and current by reading our editorial policy. We link primary sources - including studies, scientific references, and statistics - within each article and also list them in the resources section at the bottom of our articles. Medical News Today has strict sourcing guidelines and draws only from peer-reviewed studies, academic research institutions, and medical journals and associations. In addition, doctors may prescribe Lupron to treat conditions such as prostate cancer and uterine fibroids. They may take Lupron for several months to reduce endometriosis symptoms, then start trying for a pregnancy.Īlso, some fertility clinics use Lupron on an off-label basis to suppress the natural hormonal cycle before beginning treatment with in vitro fertilization, or IVF. Some women with endometriosis use Lupron to improve their chances of a successful pregnancy. A person’s treatment may involve an injection of Lupron alone or in combination with norethindrone acetate, a hormone replacement.īecause of its side effects, it is best to use Lupron for the shortest possible period.Ī doctor may recommend taking Lupron for several months before having surgery to reduce the size of the endometriosis implants. In most cases, a doctor or nurse administers the injection in a clinic. The standard dosage of Lupron for endometriosis is an intramuscular injection every month. Pregnant women and those who are trying to become pregnant should not use this drug. This means that research indicates that the drug may harm a developing fetus, possibly causing a wide range of congenital abnormalities. The FDA classify Lupron as pregnancy risk category X. People should also be aware that, in addition to potentially causing depression as a side effect, Lupron can make existing depression symptoms worse. In 2017, the Food and Drug Administration (FDA) announced an investigation into reports of severe adverse effects to assess the need for further regulation. Some bone density loss may not be reversible. If endometriosis symptoms persist, the doctor may recommend repeating treatment for 6 months in combination with a hormone replacement drug called norethindrone acetate. In people who take Lupron for endometriosis, the drug can cause additional side effects, including:īecause of the possible effects on bone density, experts recommend not taking Lupron to treat endometriosis for longer than 6 months. Lupron lowers estrogen levels in the body, typically triggering menopause-like symptoms.Īccording to the manufacturer’s clinical trials, 74% of participants who took Lupron stopped having their periods after the first month of treatment, and menstruation ceased in 98% of this group after 2 months.Īfter stopping Lupron treatment, most people find that menstruation resumes regularly within 3 months. ![]()
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